BACKGROUND:

Although the safety profile of hyaluronic acid fillers is favorable, adverse reactions can occur. Clinicians and patients can benefit from ongoing guidance on adverse reactions to hyaluronic acid fillers and their management.(雖然玻尿酸是很安全的成份, 但是醫美常用的注射玻尿酸治療偶爾還是會發生一些併發症)

METHODS:

A multinational, multidisciplinary group of experts in cosmetic medicine convened the Global Aesthetics Consensus Group to review the properties and clinical uses of Hylacross and Vycross hyaluronic acid products and develop updated consensus recommendations for early and late complications associated with hyaluronic acid fillers.

RESULTS:

The consensus panel provided specific recommendations focusing on early and late complications of hyaluronic acid fillers and their management. The impact of patient-, product-, and technique-related factors on such reactions was described. Most of these were noted to be mild and transient. Serious adverse events are rare. Early adverse reactions to hyaluronic acid fillers include vascular infarction and compromise; inflammatory reactions; injection-related events; and inappropriate placement of filler material. Among late reactions are nodules, granulomas, and skin discoloration. Most adverse events can be avoided with proper planning and technique. Detailed understanding of facial anatomy, proper patient and product selection, and appropriate technique can further reduce the risks. Should adverse reactions occur, the clinician must be prepared and have tools available for effective treatment.(跨國的醫美界組成小組來研究和監控玻尿酸造成的早期與晚期併發症。研究發現大多數的玻尿酸注射造成的不良反應都是輕微的, 而且大多數是可恢復的。嚴重的併發症, 例如血管阻塞, 失明..等, 其實發生的機率相當低。早期的不良反應包括發, 血管阻塞, 注射位置錯誤...等。晚期併發症包括產生結節, 肉芽組織, 和皮膚的色素變化等。醫師在操作前需熟知解剖和儘可能利用注射技巧和選擇玻尿酸的劑型來避免相關的併發, 以及需要對可能產生的併發症做好準備。)

CONCLUSIONS:

Adverse reactions with hyaluronic acid fillers are uncommon. Clinicians should take steps to further reduce the risk and be prepared to treat any complications that arise.